• Gene id: 57470

Gene Summary

• Gene Symbol: LRRC47   Gene   UCSC   Ensembl
• Gene name: leucine rich repeat containing 47
• Alternate names: leucine-rich repeat-containing protein 47,
• Gene location: 1p36.32 (3796497: 3778558)     Exons: 7     NC_000001.11

Protein Summary

• Protein general information: Q8N1G4  
  • Name: Leucine rich repeat containing protein 47
  • Length: 583  
  • Mass: 63473
• Sequence:

  MAAAAVSESWPELELAERERRRELLLTGPGLEERVRAAGGQLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLP
  QLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLAR
  CAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCP
  KLKEINFRGNKLRDKRLEKMVSGCQTRSILEYLRVGGRGGGKGKGRAEGSEKEESRRKRRERKQRREGGDGEEQD
  VGDAGRLLLRVLHVSENPVPLTVRVSPEVRDVRPYIVGAVVRGMDLQPGNALKRFLTSQTKLHEDLCEKRTAATL
  ATHELRAVKGPLLYCARPPQDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGNENYPC
  LVDADGDVISFPPITNSEKTKVKKTTSDLFLEVTSATSLQICKDVMDALILKMAEMKKYTLENKEEGSLSDTEAD
  AVSGQLPDPTTNPSAGKDGPSLLVVEQVRVVDLEGSLKVVYPSKADLATAPPHVTVVR

• Structural information:
  • Interpro: IPR005146  IPR001611  IPR003591  IPR032675  IPR020825  
  • Prosite: PS51450
  • STRING: ENSP00000367498
• Other Databases: GeneCards:  LRRC47  Malacards:  LRRC47

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0004826	phenylalanine-tRNA ligase activity	IEA	molecular function
GO:0003723	RNA binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)