• Gene id: 56986

Gene Summary

• Gene Symbol: DTWD1   Gene   UCSC   Ensembl
• Aliases: MDS009
• Gene name: DTW domain containing 1
• Alternate names: DTW domain-containing protein 1, x 009 protein,
• Gene location: 15q21.2 (49621021: 49656231)     Exons: 10     NC_000015.10
• OMIM: 0

Protein Summary

• Protein general information: Q8N5C7  
  • Name: DTW domain containing protein 1
  • Length: 304  
  • Mass: 35248
• Sequence:

  MSLNPPIFLKRSEENSSKFVETKQSQTTSIASEDPLQNLCLASQEVLQKAQQSGRSKCLKCGGSRMFYCYTCYVP
  VENVPIEQIPLVKLPLKIDIIKHPNETDGKSTAIHAKLLAPEFVNIYTYPCIPEYEEKDHEVALIFPGPQSISIK
  DISFHLQKRIQNNVRGKNDDPDKPSFKRKRTEEQEFCDLNDSKCKGTTLKKIIFIDSTWNQTNKIFTDERLQGLL
  QVELKTRKTCFWRHQKGKPDTFLSTIEAIYYFLVDYHTDILKEKYRGQYDNLLFFYSFMYQLIKNAKCSGDKETG
  KLTH

• Structural information:
  • Interpro: IPR005636  
  • STRING: ENSP00000251250
• Other Databases: GeneCards:  DTWD1  Malacards:  DTWD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016432	tRNA-uridine aminocarboxypropyltransferase activity	IDA	molecular function
GO:0005634	nucleus	IDA	cellular component
GO:0006400	tRNA modification	IDA	biological process
GO:0016740	transferase activity	IEA	molecular function
GO:0008033	tRNA processing	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0016432	tRNA-uridine aminocarboxypropyltransferase activity	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)