• Gene id: 56952

Gene Summary

• Gene Symbol: PRTFDC1   Gene   UCSC   Ensembl
• Aliases: HHGP
• Gene name: phosphoribosyl transferase domain containing 1
• Alternate names: phosphoribosyltransferase domain-containing protein 1,
• Gene location: 10p12.1 (24952605: 24848613)     Exons: 9     NC_000010.11
• OMIM: 147851

Protein Summary

• Protein general information: Q9NRG1  
  • Name: Phosphoribosyltransferase domain containing protein 1
  • Length: 225  
  • Mass: 25674
• Sequence:

  MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLCVL
  KGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLAGKNVLIVEDVVGTGRTM
  KALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV

• Structural information:
  • Interpro: IPR005904  IPR000836  IPR029057  
  • CDD: cd06223
  • PDB: 2JBH
  • PDBsum: 2JBH
  • STRING: ENSP00000318602
• Other Databases: GeneCards:  PRTFDC1  Malacards:  PRTFDC1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046038	GMP catabolic process	IDA	NOT|biological process
GO:0006178	guanine salvage	IDA	NOT|biological process
GO:0004422	hypoxanthine phosphoribosyltransferase activity	IDA	NOT|molecular function
GO:0042803	protein homodimerization activity	IPI	molecular function
GO:0000287	magnesium ion binding	TAS	molecular function
GO:0006166	purine ribonucleoside salvage	IEA	biological process
GO:0009116	nucleoside metabolic process	IEA	biological process
GO:0046872	metal ion binding	IEA	molecular function
GO:0000166	nucleotide binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881