• Gene id: 56901

Gene Summary

• Gene Symbol: NDUFA4L2   Gene   UCSC   Ensembl
• Aliases: COXFA4L2, NUOMS
• Gene name: NDUFA4 mitochondrial complex associated like 2
• Alternate names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2, NADH:ubiquinone oxidoreductase MLRQ subunit homolog, cytochrome c oxidase subunit FA4 like 2,
• Gene location: 12q13.3 (57240761: 57234902)     Exons: 5     NC_000012.12
• OMIM: 181590

Protein Summary

• Protein general information: Q9NRX3  
  • Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 like 2 (NADH ubiquinone oxidoreductase MLRQ subunit homolog) (NUOMS)
  • Length: 87  
  • Mass: 9966
• Sequence:

  MAGASLGARFYRQIKRHPGIIPMIGLICLGMGSAALYLLRLALRSPDVCWDRKNNPEPWNRLSPNDQYKFLAVST
  DYKKLKKDRPDF

• Structural information:
  • Interpro: IPR010530  
  • STRING: ENSP00000377411
• Other Databases: GeneCards:  NDUFA4L2  Malacards:  NDUFA4L2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0004129	cytochrome-c oxidase activity	IBA	contributes to
GO:0005751	mitochondrial respiratory chain complex IV	IBA	cellular component
GO:1902600	proton transmembrane transport	IEA	biological process
GO:0022900	electron transport chain	IEA	biological process

KEGG pathways

Pathway id	Pathway name
hsa01100	Metabolic pathways
hsa05010	Alzheimer disease
hsa05016	Huntington disease
hsa05012	Parkinson disease
hsa04714	Thermogenesis
hsa04723	Retrograde endocannabinoid signaling
hsa00190	Oxidative phosphorylation
hsa04932	Non-alcoholic fatty liver disease

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881