• Gene id: 55700

Gene Summary

• Gene Symbol: MAP7D1   Gene   UCSC   Ensembl
• Aliases: PARCC1, RPRC1
• Gene name: MAP7 domain containing 1
• Alternate names: MAP7 domain-containing protein 1, arginine/proline rich coiled-coil 1, arginine/proline-rich coiled-coil domain-containing protein 1, proline arginine rich coiled coil 1, proline/arginine-rich coiled-coil domain-containing protein 1,
• Gene location: 1p34.3 (36156149: 36180848)     Exons: 17     NC_000001.11

Protein Summary

• Protein general information: Q3KQU3  
  • Name: MAP7 domain containing protein 1 (Arginine/proline rich coiled coil domain containing protein 1) (Proline/arginine rich coiled coil domain containing protein 1)
  • Length: 841  
  • Mass: 92820
• Sequence:

  MESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQV
  GPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERA
  KYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAE
  IRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRL
  MTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSV
  TRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRAR
  LSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPED
  KSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEAT
  RLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQ
  KEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVE
  ARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGPSGDKSLSRTPETLLPFAEAEA
  FLKKAVVQSPQVTEVL

• Structural information:
  • Interpro: IPR008604  
  • STRING: ENSP00000362244
• Other Databases: GeneCards:  MAP7D1  Malacards:  MAP7D1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0015630	microtubule cytoskeleton	IBA	cellular component
GO:0000226	microtubule cytoskeleton organization	IBA	biological process
GO:0015630	microtubule cytoskeleton	IEA	cellular component
GO:0000226	microtubule cytoskeleton organization	IEA	biological process
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005819	spindle	IEA	cellular component
GO:0005829	cytosol	IDA	cellular component
GO:0015630	microtubule cytoskeleton	IDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray