• Gene id: 55653

Gene Summary

• Gene Symbol: BCAS4   Gene   UCSC   Ensembl
• Aliases: CNOL
• Gene name: breast carcinoma amplified sequence 4
• Alternate names: breast carcinoma-amplified sequence 4, BCAS4/BCAS3 fusion, breast carcinoma amplified sequence 4/3 fusion protein,
• Gene location: 20q13.13 (50794893: 50877735)     Exons: 9     NC_000020.11
• OMIM: 612809

Protein Summary

• Protein general information: Q8TDM0  
  • Name: Breast carcinoma amplified sequence 4
  • Length: 211  
  • Mass: 22758
  • Tissue specificity: Brain, thymus, spleen, kidney and placenta. Overexpressed in most breast cancer cell lines. {ECO
• Sequence:

  MQRTGGGAPRPGRNHGLPGSLRQPDPVALLMLLVDADQPEPMRSGARELALFLTPEPGAEAKEVEETIEGMLLRL
  EEFCSLADLIRSDTSQILEENIPVLKAKLTEMRGIYAKVDRLEAFVKMVGHHVAFLEADVLQAERDHGAFPQALR
  RWLGSAGLPSFRNVECSGTIPARCNLRLPGSSDSPASASQVAGITEVTCTGARDVRAAHTV

• Structural information:
  • Interpro: IPR024857  
  • STRING: ENSP00000351642
• Other Databases: GeneCards:  BCAS4  Malacards:  BCAS4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0031083	BLOC-1 complex	IBA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq