|
Gene id |
55521 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TRIM36 Gene UCSC Ensembl |
|
Aliases |
ANPH, HAPRIN, RBCC728, RNF98 |
|
Gene name |
tripartite motif containing 36 |
|
Alternate names |
E3 ubiquitin-protein ligase TRIM36, RING finger protein 98, RING-type E3 ubiquitin transferase TRIM36, tripartite motif protein 36, tripartite motif-containing protein 36, zinc-binding protein Rbcc728, |
|
Gene location |
5q22.3 (115180545: 115124771) Exons: 16 NC_000005.10
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants
|
|
OMIM |
609317 |
|
| Associated diseases |
References |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Associated with acrosome reaction and fertilization | MIK: 12917430 |
| Hypospermatogenesis | MIK: 28361989 |
| Non obstructive azoospermia | MIK: 24012201 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Plays an important role in acrosome reaction | MIK: 15955891 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 15955891 |
Plays an i
mportant r
ole in acr
osome reac
tion
|
|
|
|
Male infertility |
|
Show abstract |
| 12917430 |
Assocaited
with acro
some react
ion and fe
rtilizatio
n
|
|
|
|
Male infertility |
|
Show abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|