• Gene id: 55313

Gene Summary

• Gene Symbol: CPPED1   Gene   UCSC   Ensembl
• Aliases: CSTP1
• Gene name: calcineurin like phosphoesterase domain containing 1
• Alternate names: serine/threonine-protein phosphatase CPPED1, calcineurin-like phosphoesterase domain-containing protein 1, complete S-transactivated protein 1,
• Gene location: 16p13.12 (12803886: 12659798)     Exons: 4     NC_000016.10
• OMIM: 612373

Protein Summary

• Protein general information: Q9BRF8  
  • Name: Serine/threonine protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin like phosphoesterase domain containing protein 1) (Complete S transactivated protein 1)
  • Length: 314  
  • Mass: 35548
  • Tissue specificity: Expressed in subcutaneous adipose tissue. {ECO
• Sequence:

  MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDEWEQEIRLTEQAVQAI
  NKLNPKPKFFVLCGDLIHAMPGKPWRTEQTEDLKRVLRAVDRAIPLVLVSGNHDIGNTPTAETVEEFCRTWGDDY
  FSFWVGGVLFLVLNSQFYENPSKCPSLKQAQDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDDDYYFNLSK
  STRKKLADKFIHAGVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKIVHRYYSLDELSE
  KGIEDDLMDLIKKK

• Structural information:
  • Interpro: IPR004843  IPR029052  IPR041867  
  • CDD: cd07395
  • STRING: ENSP00000371193
• Other Databases: GeneCards:  CPPED1  Malacards:  CPPED1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016787	hydrolase activity	IEA	molecular function
GO:0016787	hydrolase activity	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0004721	phosphoprotein phosphatase activity	IEA	molecular function
GO:0043312	neutrophil degranulation	TAS	biological process
GO:0005576	extracellular region	TAS	cellular component
GO:0035578	azurophil granule lumen	TAS	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005886	plasma membrane	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component
GO:0006470	protein dephosphorylation	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq