• Gene id: 55287

Gene Summary

• Gene Symbol: TMEM40   Gene   UCSC   Ensembl
• Gene name: transmembrane protein 40
• Alternate names: transmembrane protein 40,
• Gene location: 3p25.2 (12769456: 12733527)     Exons: 14     NC_000003.12
• OMIM: 0

Protein Summary

• Protein general information: Q8WWA1  
  • Name: Transmembrane protein 40
  • Length: 233  
  • Mass: 25495
• Sequence:

  METSASSSQPQDNSQVHRETEDVDYGETDFHKQDGKAGLFSQEQYERNKSSSSSSSSSSSSSSSSSSSSSESNDE
  DQQPRATGKHRRSLGAGYPHGNGSPGPGHGEPDVLKDELQLYGDAPGEVVPSGESGLRRRGSDPASGEVEASQLR
  RLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLQGFIPLFQKFR
  LTGFRKTD

• Structural information:
  • Interpro: IPR026181  
  • STRING: ENSP00000322837
• Other Databases: GeneCards:  TMEM40  Malacards:  TMEM40

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq