|
Gene id |
5524 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PTPA Gene UCSC Ensembl |
|
Aliases |
PP2A, PPP2R4, PR53 |
|
Gene name |
protein phosphatase 2 phosphatase activator |
|
Alternate names |
serine/threonine-protein phosphatase 2A activator, PP2A phosphatase activator, PP2A subunit B' isoform PR53, phosphotyrosyl phosphatase activator, protein phosphatase 2 regulatory subunit 4, protein phosphatase 2A activator, regulatory subunit 4, protein phosph, |
|
Gene location |
9q34.11 (129110948: 129148945) Exons: 13 NC_000005.10
|
|
Gene summary(Entrez) |
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subu
|
|
OMIM |
600756 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
|
|
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| Associated diseases |
References |
| Chronic renal failure | GAD: 21085059 |
| Spermatogenesis defects | MIK: 25628439 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenesis defects, Male infertility | MIK: 25628439 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25628439 |
Spermatoge
nesis defe
cts, Male
infertilit
y
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|