• Gene id: 55119

Gene Summary

• Gene Symbol: PRPF38B   Gene   UCSC   Ensembl
• Aliases: NET1
• Gene name: pre-mRNA processing factor 38B
• Alternate names: pre-mRNA-splicing factor 38B, PRP38 pre-mRNA processing factor 38 domain containing B, sarcoma antigen NY-SAR-27,
• Gene location: 1p13.3 (108692309: 108702927)     Exons: 8     NC_000001.11
• OMIM: 611910

Protein Summary

• Protein general information: Q5VTL8  
  • Name: Pre mRNA splicing factor 38B (Sarcoma antigen NY SAR 27)
  • Length: 546  
  • Mass: 64468
• Sequence:

  MANNSPALTGNSQPQHQAAAAAAQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQ
  LYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLIT
  HTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPV
  QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE
  RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERG
  NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS
  RSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRR
  RSQSIEQESQEKQHKNKDETV

• Structural information:
  • Interpro: IPR005037  
  • STRING: ENSP00000359042
• Other Databases: GeneCards:  PRPF38B  Malacards:  PRPF38B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0071011	precatalytic spliceosome	IBA	cellular component
GO:0005681	spliceosomal complex	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0006397	mRNA processing	IEA	biological process
GO:0008380	RNA splicing	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0003723	RNA binding	HDA	molecular function

KEGG pathways

Pathway id	Pathway name
hsa03040	Spliceosome

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881