• Gene id: 54853

Gene Summary

• Gene Symbol: WDR55   Gene   UCSC   Ensembl
• Gene name: WD repeat domain 55
• Alternate names: WD repeat-containing protein 55,
• Gene location: 5q31.3 (140664798: 140674118)     Exons: 9     NC_000005.10
• OMIM: 0

Protein Summary

• Protein general information: Q9H6Y2  
  • Name: WD repeat containing protein 55
  • Length: 383  
  • Mass: 42070
• Sequence:

  MDRTCEERPAEDGSDEEDPDSMEAPTRIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGETK
  ELWSSGHHLKACRAVAFSEDGQKLITVSKDKAIHVLDVEQGQLERRVSKAHGAPINSLLLVDENVLATGDDTGGI
  CLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGIFNIKRRRFELLSEPQSGDLTSVTLMKWGKKV
  ACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTESLLCTGSTDGVIRAVNILPNRVVGSVGQHTGEPVEE
  LALSHCGRFLASSGHDQRLKFWDMAQLRAVVVDDYRRRKKKGGPLRALSSKTWSTDDFFAGLREEGEDSMAQEEK
  EETGDDSD

• Structural information:
  • Interpro: IPR024977  IPR015943  IPR001680  IPR019775  IPR017986   IPR036322  IPR017422  
  • Prosite: PS00678 PS50082 PS50294
  • STRING: ENSP00000351100
• Other Databases: GeneCards:  WDR55  Malacards:  WDR55

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005730	nucleolus	ISS	cellular component
GO:0006364	rRNA processing	ISS	biological process
GO:0006364	rRNA processing	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0006364	rRNA processing	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005730	nucleolus	IEA	cellular component
GO:0005730	nucleolus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0008150	biological_process	ND	biological process
GO:0003674	molecular_function	ND	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray