|
Gene id |
5460 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
POU5F1 Gene UCSC Ensembl |
|
Aliases |
OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 |
|
Gene name |
POU class 5 homeobox 1 |
|
Alternate names |
POU domain, class 5, transcription factor 1, POU class 5 homeobox 1 transcript variant OCT4B1, POU class 5 homeobox 1 transcript variant OCT4B2, POU class 5 homeobox 1 transcript variant OCT4B3, POU class 5 homeobox 1 transcript variant OCT4B4, POU class 5 ho, |
|
Gene location |
6p21.33 (31170681: 31164336) Exons: 6 NC_000006.12
|
|
Gene summary(Entrez) |
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate
|
|
OMIM |
164177 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04550 | Signaling pathways regulating pluripotency of stem cells | |
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| Associated diseases |
References |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Have a regulatory role in control of meiosis and/or terminal differentiation of spermatogenic cells | MIK: 9163102 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 9163102 |
Have a reg
ulatory ro
le in con
trol of me
iosis and/
or termina
l differen
tiation of
spermatog
enic cells
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|