|
Gene id |
5270 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
SERPINE2 Gene UCSC Ensembl |
|
Aliases |
GDN, GDNPF, PI-7, PI7, PN-1, PN1, PNI |
|
Gene name |
serpin family E member 2 |
|
Alternate names |
glia-derived nexin, glial-derived neurite promoting factor, peptidase inhibitor 7, protease nexin I, serpin E2, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2, |
|
Gene location |
2q36.1 (224039318: 223975047) Exons: 13 NC_000002.12
|
|
Gene summary(Entrez) |
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for ch
|
|
OMIM |
177010 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Cancer (lung) | GAD: 19789190 |
| Hepatopulmonary syndrome | GAD: 17934860 |
| Celiac disease | GAD: 19626039 |
| Sperm decapacitation | MIK: 21084713 |
| Chronic obstructive pulmonary disease (COPD) | GAD: 17446335 |
| Pulmonary emphysema | GAD: 21067581 |
| Anoxia | GAD: 19017876 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Sperm decapacitation factor | MIK: 21084713 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 21084713 |
Sperm deca
pacitation
factor
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|