• Gene id: 51249

Gene Summary

• Gene Symbol: TMEM69   Gene   UCSC   Ensembl
• Aliases: C1orf154
• Gene name: transmembrane protein 69
• Alternate names: transmembrane protein 69,
• Gene location: 1p34.1 (84241545: 84231519)     Exons: 5     NC_000010.11

Protein Summary

• Protein general information: Q5SWH9  
  • Name: Transmembrane protein 69
  • Length: 247  
  • Mass: 27551
• Sequence:

  MLRFIQKFSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTSPCSFKKQQ
  KQALLARPSSTITYLTDSPKPALCVTLAGLIPFVAPPLVMLMTKTYIPILAFTQMAYGASFLSFLGGIRWGFALP
  EGSPAKPDYLNLASSAAPLFFSWFAFLISERLSEAIVTVIMGMGVAFHLELFLLPHYPNWFKALRIVVTLLATFS
  FIITLVVKSSFPEKGHKRPGQV

• Structural information:
  • Interpro: IPR021836  
  • STRING: ENSP00000361095
• Other Databases: GeneCards:  TMEM69  Malacards:  TMEM69

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)