• Gene id: 51015

Gene Summary

• Gene Symbol: ISOC1   Gene   UCSC   Ensembl
• Aliases: CGI-111
• Gene name: isochorismatase domain containing 1
• Alternate names: isochorismatase domain-containing protein 1,
• Gene location: 5q23.3 (129094748: 129114027)     Exons: 5     NC_000005.10
• OMIM: 0

Protein Summary

• Protein general information: Q96CN7  
  • Name: Isochorismatase domain containing protein 1
  • Length: 298  
  • Mass: 32237
• Sequence:

  MAAAEPAVLALPNSGAGGAGAPSGTVPVLFCFSVFARPSSVPHGAGYELLIQKFLSLYGDQIDMHRKFVVQLFAE
  EWGQYVDLPKGFAVSERCKVRLVPLQIQLTTLGNLTPSSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARIL
  GIPVIVTEQYPKGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEAALAEIPGVRSVVLFGVETHVCIQQTALELVG
  RGVEVHIVADATSSRSMMDRMFALERLARTGIIVTTSEAVLLQLVADKDHPKFKEIQNLIKASAPESGLLSKV

• Structural information:
  • Interpro: IPR000868  IPR036380  
  • STRING: ENSP00000173527
• Other Databases: GeneCards:  ISOC1  Malacards:  ISOC1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005777	peroxisome	ISS	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0003824	catalytic activity	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0003674	molecular_function	ND	molecular function
GO:0008150	biological_process	ND	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)