|
Gene id |
50674 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
NEUROG3 Gene UCSC Ensembl |
|
Aliases |
Atoh5, Math4B, NGN-3, bHLHa7, ngn3 |
|
Gene name |
neurogenin 3 |
|
Alternate names |
neurogenin-3, class A basic helix-loop-helix protein 7, protein atonal homolog 5, |
|
Gene location |
10q22.1 (69573424: 69571439) Exons: 2 NC_000004.12
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive dia
|
|
OMIM |
604882 |
|
| Pathway id | Pathway name |
|---|
| hsa04950 | Maturity onset diabetes of the young | | hsa04950 | Maturity onset diabetes of the young | |
|
| Associated diseases |
References |
| Coronary heart disease | GAD: 19336475 |
| Diabetes | GAD: 17146417 |
| Spermatogenesis defects | MIK: 22378757 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Regulates differentiation of mammalian stem and progenitor spermatogonia. | MIK: 22378757 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 22378757 |
Regulates
differenti
ation of m
ammalian s
tem and pr
ogenitor s
permatogon
ia.
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|