• Gene id: 497190

Gene Summary

• Gene Symbol: CLEC18B   Gene   UCSC   Ensembl
• Aliases: MRCL2
• Gene name: C-type lectin domain family 18 member B
• Alternate names: C-type lectin domain family 18 member B, mannose receptor-like 2, mannose receptor-like protein 1, secretory protein LOC497190,
• Gene location: 16q23.1 (74422247: 74408630)     Exons: 15     NC_000016.10
• OMIM: 164340

Protein Summary

• Protein general information: Q6UXF7  
  • Name: C type lectin domain family 18 member B (Mannose receptor like protein 1)
  • Length: 455  
  • Mass: 50490
• Sequence:

  MLHPETSPGRGHLLAVLLALLGTTWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWS
  DSLAQLAQARAALCGIPTPSLASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHY
  TQLVWATSSQLGCGRHLCSAGQTAIEAFVCAYSPGGNWEVNGKTIIPYKKGAWCSLCTASVSGCFKAWDHAGGLC
  EVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH
  TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTY
  KTAKDSFRWATGEHQAFTSFAFGQPDNHGLVWLSAAMGFGNCVELQASAAFNWNDQRCKTRNRYICQFAQEHISR
  WGPGS

• Structural information:
  • Protein Domains: (52..18-)
    (/note="SCP-)
    (228..26-)
    (/note="EGF-like-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00076-)
    (306..44-)
    (/note="C-type-lectin)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00040"-)
  • Interpro: IPR001304  IPR016186  IPR018378  IPR014044  IPR035940   IPR001283  IPR016187  IPR013032  IPR000742  
  • Prosite: PS00615 PS50041 PS00022 PS01186 PS50026
  • STRING: ENSP00000341051
• Other Databases: GeneCards:  CLEC18B  Malacards:  CLEC18B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005615	extracellular space	IBA	cellular component
GO:0030247	polysaccharide binding	IBA	molecular function
GO:0016529	sarcoplasmic reticulum	TAS	cellular component
GO:0005794	Golgi apparatus	TAS	cellular component
GO:0005768	endosome	TAS	cellular component
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0005768	endosome	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0030246	carbohydrate binding	IEA	molecular function
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0005768	endosome	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq