|
Gene id |
4602 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MYB Gene UCSC Ensembl |
|
Aliases |
Cmyb, c-myb, c-myb_CDS, efg |
|
Gene name |
MYB proto-oncogene, transcription factor |
|
Alternate names |
transcriptional activator Myb, oncogene AMV, proto-oncogene c-Myb, v-myb avian myeloblastosis viral oncogene homolog, |
|
Gene location |
6q23.3 (135181307: 135219172) Exons: 19 NC_000019.10
|
|
Gene summary(Entrez) |
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocati
|
|
OMIM |
189990 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa00140 | Steroid hormone biosynthesis | | hsa04151 | PI3K-Akt signaling pathway | | hsa04151 | PI3K-Akt signaling pathway | |
|
| Associated diseases |
References |
| Cancer (salivary gland) | KEGG: H01508 |
| Hypertension | GAD: 19862010 |
| Coronary heart disease | GAD: 15221349 |
| Myocardial Infarction | GAD: 19198610 |
| Peripheral vascular disease | GAD: 20927387 |
| Alpha-thalassemia | GAD: 19696200 |
| Sickle cell anemia | GAD: 19148297 |
| Obesity | GAD: 20816195 |
| Associated with mouse spermatogenesis | MIK: 20003220 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Associated with mouse spermatogenesis | MIK: 20003220 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 20003220 |
Associated
with mous
e spermato
genesis
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|