• Gene id: 440836

Gene Summary

• Gene Symbol: ODF3B   Gene   UCSC   Ensembl
• Aliases: FAP123, ODF3L3
• Gene name: outer dense fiber of sperm tails 3B
• Alternate names: outer dense fiber protein 3B, orf2 5' to PD-ECGF/TP, outer dense fiber protein 3-like protein 3,
• Gene location: 22q13.33 (50532578: 50530408)     Exons: 11     NC_000022.11

Protein Summary

• Protein general information: A8MYP8  
  • Name: Outer dense fiber protein 3B (Outer dense fiber protein 3 like protein 3)
  • Length: 253  
  • Mass: 27280
• Sequence:

  MGSDAWVGLWRPHRPRGPIAAHYGGPGPKYKLPPNTGYALHDPSRPRAPAFTFGARFPTQQTTCGPGPGHLVPAR
  MTVRGTDGAPAYSIYGRPRRSAPFLTPGPGRYFPERAGNATYPSAPRHTIAPRNWGVQAEQQSPGPAAYTVPSLL
  GPRVIGKVSAPTCSIYGRRAAGSFFEDLSKTPGPCAYQVVSPGVYKSRAPQFTILARTSLPQDNTRKPGPAAYNV
  DQHRKPRGWSFGIRHSDYLAPLVTDADN

• Structural information:
  • Interpro: IPR010736  
  • STRING: ENSP00000382804
• Other Databases: GeneCards:  ODF3B  Malacards:  ODF3B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005856	cytoskeleton	IBA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 21412036
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21412036	Cryptorchidism			23 (4 controls, 19 cases)	Male infertility	GSE25518 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq