• Gene id: 440730

Gene Summary

• Gene Symbol: TRIM67   Gene   UCSC   Ensembl
• Aliases: TNL
• Gene name: tripartite motif containing 67
• Alternate names: tripartite motif-containing protein 67, TRIM9-like protein TNL,
• Gene location: 1q42.2 (231162390: 231221564)     Exons: 10     NC_000001.11

Protein Summary

• Protein general information: Q6ZTA4  
  • Name: Tripartite motif containing protein 67 (TRIM9 like protein)
  • Length: 783  
  • Mass: 83823
• Sequence:

  MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAGAAAAASLEHDAAAGP
  ACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSL
  SSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQ
  CDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF
  PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNI
  LQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKE
  NDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCT
  RNNSVTLAWRMPPFTHSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTV
  VLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASV
  VKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGV
  FMPALSLNRNVQVTLHTGLEVPTNLGRPKLSGN

• Structural information:
  • Protein Domains: (448..50-)
    (/note="COS-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00586-)
    (513..60-)
    (/note="Fibronectin-type-III)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00316-)
    (589..78-)
    (/note="B30.2/SPRY-)
    (/evidence="ECO:0000255|PROSITE-ProR-)
  • Interpro: IPR001870  IPR003649  IPR013320  IPR017903  IPR003961   IPR036116  IPR013783  IPR003877  IPR000315  IPR018957  IPR001841  IPR013083  IPR017907  
  • Prosite: PS50188 PS51262 PS50853 PS50119 PS00518
  • CDD: cd00021 cd00063
  • STRING: ENSP00000355613
• Other Databases: GeneCards:  TRIM67  Malacards:  TRIM67

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:1903827	regulation of cellular protein localization	ISS	biological process
GO:0008270	zinc ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0010976	positive regulation of neuron projection development	IEA	biological process
GO:0046580	negative regulation of Ras protein signal transduction	IEA	biological process
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq