• Gene id: 402665

Gene Summary

• Gene Symbol: IGLON5   Gene   UCSC   Ensembl
• Gene name: IgLON family member 5
• Alternate names: igLON family member 5, Ig-like domain-containing protein ENSP00000270642, hCG1651476,
• Gene location: 19q13.41 (51311847: 51330867)     Exons: 8     NC_000019.10
• OMIM: 611692

Protein Summary

• Protein general information: A6NGN9  
  • Name: IgLON family member 5
  • Length: 336  
  • Mass: 36795
• Sequence:

  MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAG
  NDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNV
  NLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTS
  ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS
  SASMRLLRPGSLENSAPRPPGLLALLSALGWLWWRM

• Structural information:
  • Protein Domains: (33..12-)
    1 (/note="Ig-like-C2-type)
    (132..21-)
    2 (/note="Ig-like-C2-type)
    (218..30-)
    3" (/note="Ig-like-C2-type)
  • Interpro: IPR007110  IPR036179  IPR013783  IPR003599  IPR003598   IPR013151  
  • Prosite: PS50835
  • PDB: 6DLD 6DLE
  • PDBsum: 6DLD 6DLE
  • STRING: ENSP00000270642
• Other Databases: GeneCards:  IGLON5  Malacards:  IGLON5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray