• Gene id: 401944

Gene Summary

• Gene Symbol: LDLRAD2   Gene   UCSC   Ensembl
• Gene name: low density lipoprotein receptor class A domain containing 2
• Alternate names: low-density lipoprotein receptor class A domain-containing protein 2, low density lipoprotein receptor A domain containing 2,
• Gene location: 1p36.12 (21812208: 21825224)     Exons: 5     NC_000001.11
• OMIM: 618861

Protein Summary

• Protein general information: Q5SZI1  
  • Name: Low density lipoprotein receptor class A domain containing protein 2
  • Length: 272  
  • Mass: 28581
• Sequence:

  MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAPDTDCGLWVQAAAPGD
  RIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRL
  VTRGRQPRVDFVGEVTSFRLGPCGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGS
  TDAHTSRSLTPSPALGSAGSLWIAAERSSPAGRDPTRQDAALEGSTE

• Structural information:
  • Protein Domains: (172..21-)
    A (/note="LDL-receptor-class)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00124"-)
  • Interpro: IPR036055  IPR042333  IPR002172  IPR035914  
  • Prosite: PS50068
  • CDD: cd00112
  • STRING: ENSP00000340988
• Other Databases: GeneCards:  LDLRAD2  Malacards:  LDLRAD2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq