• Gene id: 401612

Gene Summary

• Gene Symbol: SLC25A53   Gene   UCSC   Ensembl
• Aliases: MCART6
• Gene name: solute carrier family 25 member 53
• Alternate names: solute carrier family 25 member 53, mitochondrial carrier triple repeat protein 6,
• Gene location: Xq22.2 (104157008: 104099213)     Exons: 18     NC_000023.11
• OMIM: 300941

Protein Summary

• Protein general information: Q5H9E4  
  • Name: Solute carrier family 25 member 53 (Mitochondrial carrier triple repeat protein 6)
  • Length: 307  
  • Mass: 34481
• Sequence:

  MGEQNHSPGKELQHRTRAEAPGKKSWHSQAYALGAVSNFMSTFLTFPIYKVVFRQQIHAMAVSEAVRQLWHEGPQ
  YFYRGIYPPLLSKTLQGTLLFGTYDSLLCFLSPVGPHTLGHRWAAGLMSGVVEAVALSPFERVQNVLQDGRKQAR
  FPSTFSILKEFNSYGLWGRLSLGYYRGFWPVLARNSLGSALYFSFKDPIQDGLAEQGLPHWVPALVSGSVNGTIT
  CLVLYPLIVLVANMQSHIGWQNMPSLWASAQDVWNTRGRKLLLIYRGGSLVILRSSVTWGLTTAIHDFLQRKSHS
  RKELKTD

• Structural information:
  • Interpro: IPR018108  IPR023395  
  • Prosite: PS50920
  • STRING: ENSP00000468980
• Other Databases: GeneCards:  SLC25A53  Malacards:  SLC25A53

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005743	mitochondrial inner membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005739	mitochondrion	IEA	cellular component
GO:0005743	mitochondrial inner membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)