• Gene id: 401387

Gene Summary

• Gene Symbol: LRRD1   Gene   UCSC   Ensembl
• Gene name: leucine rich repeats and death domain containing 1
• Alternate names: leucine-rich repeat and death domain-containing protein 1, leucine-rich repeat and death domain-containing protein LOC401387,
• Gene location: 7q21.2 (92165275: 92144883)     Exons: 5     NC_000007.14
• OMIM: 0

Protein Summary

• Protein general information: A4D1F6  
  • Name: Leucine rich repeat and death domain containing protein 1
  • Length: 860  
  • Mass: 98035
• Sequence:

  MSEKEGMSEVLEDTISQFRKESRSQSMKEPGFIKETSNLINEASDYLEGKSSNQIYETHPRQNTLESTSSSGRKS
  KRNEEQKKNLQFSETSTRTGTSQSLSSLTGRTAEYQALVNFLSHETVGEVSPQVSEENQKQLGLGADNFTVNLEA
  KGLQEFPKDILKIKYVKYLYLDKNQIKTFQGADSGDLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISH
  IPKEISQLGNIRQLFFYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALC
  FLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNKLEVISHKIENFRELR
  ILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNLRKLHVNRNNMVKITDCISHLNNICSLEFSG
  NIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIF
  SEHFCSLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICN
  LKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRN
  LVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNPLLRPPVEICKGKQLYTIAR
  YLQRADERDEKILEKIFKIVANNITETNFEFLCQKLNLANSETDMPTKSTVSLSERAHQALVIWKTQSNKLSLTA
  AALRDQLIRALTMIGAYEIMDKITALNLFTRAIKF

• Structural information:
  • Protein Domains: (764..85-)
    (/note="Death-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00064"-)
  • Interpro: IPR000488  IPR001611  IPR003591  IPR032675  
  • Prosite: PS50017 PS51450
  • STRING: ENSP00000405987
• Other Databases: GeneCards:  LRRD1  Malacards:  LRRD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007165	signal transduction	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)