• Gene id: 400745

Gene Summary

• Gene Symbol: SH2D5   Gene   UCSC   Ensembl
• Gene name: SH2 domain containing 5
• Alternate names: SH2 domain-containing protein 5,
• Gene location: 1p36.12 (20732702: 20719730)     Exons: 13     NC_000001.11
• OMIM: 618216

Protein Summary

• Protein general information: Q6ZV89  
  • Name: SH2 domain containing protein 5
  • Length: 423  
  • Mass: 46797
• Sequence:

  MQKAGAGGRRASDCGLAPHRPRCITKFAQYVGSFPVDDLDTQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKI
  YSGEGEVLLMAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQH
  PEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKELPESEGRARHARL
  GNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAG
  ISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVT
  ERSLFCPLDMGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG

• Structural information:
  • Protein Domains: (296..39-)
    (/note="SH2-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00191"-)
  • Interpro: IPR011993  IPR006020  IPR000980  IPR036860  
  • Prosite: PS50001
  • STRING: ENSP00000406026
• Other Databases: GeneCards:  SH2D5  Malacards:  SH2D5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0014069	postsynaptic density	ISS	cellular component
GO:0030054	cell junction	IEA	cellular component
GO:0045202	synapse	IEA	cellular component
GO:0014069	postsynaptic density	IEA	cellular component
GO:0014069	postsynaptic density	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq