• Gene id: 389206

Gene Summary

• Gene Symbol: BEND4   Gene   UCSC   Ensembl
• Aliases: CCDC4
• Gene name: BEN domain containing 4
• Alternate names: BEN domain-containing protein 4, coiled-coil domain containing 4, coiled-coil domain-containing protein 4,
• Gene location: 4p13 (42152654: 42110852)     Exons: 5     NC_000004.12

Protein Summary

• Protein general information: Q6ZU67  
  • Name: BEN domain containing protein 4 (Coiled coil domain containing protein 4)
  • Length: 534  
  • Mass: 58375
• Sequence:

  MEEEMQPAEEGPSVPKIYKQRSPYSVLKTFPSKRPALAKRYERPTLVELPHVRAPPPPPPPFAPHAAVSISSSEP
  PPQQFQAQSSYPPGPGRAAAAASSSSPSCTPATSQGHLRTPAQPPPASPAASSSSSFAAVVRYGPGAAAAAGTGG
  TGSDSASLELSAESRMILDAFAQQCSRVLSLLNCGGKLLDSNHSQSMISCVKQEGSSYNERQEHCHIGKGVHSQT
  SDNVDIEMQYMQRKQQTSAFLRVFTDSLQNYLLSGSFPTPNPSSASEYGHLADVDPLSTSPVHTLGGWTSPATSE
  SHGHPSSSTLPEEEEEEDEEGYCPRCQELEQEVISLQQENEELRRKLESIPVPCQTVLDYLKMVLQHHNQLLIPQ
  PADQPTEGSKQLLNNYPVYITSKQWDEAVNSSKKDGRRLLRYLIRFVFTTDELKYSCGLGKRKRSVQSGETGPER
  RPLDPVKVTCLREFIRMHCTSNPDWWMPSEEQINKVFSDAVGHARQGRAVGTFLHNGGSFYEGIDHQASQDEVFN
  KSSQDGSGD

• Structural information:
  • Protein Domains: (390..49-)
    (/note="BEN-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00784"-)
  • Interpro: IPR018379  IPR038950  
  • Prosite: PS51457
  • STRING: ENSP00000421169
• Other Databases: GeneCards:  BEND4  Malacards:  BEND4

Diseases

Associated diseases	References
Cryptorchidism	MIK: 21412036

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21412036	Cryptorchidism			23 (4 controls, 19 cases)	Male infertility	GSE25518 analyzed by GEO2R (cutoff 1.5 fold)