• Gene id: 388335

Gene Summary

• Gene Symbol: TMEM220   Gene   UCSC   Ensembl
• Gene name: transmembrane protein 220
• Alternate names: transmembrane protein 220,
• Gene location: 17p13.1 (71808833: 71728999)     Exons: 24     NC_000016.10

Protein Summary

• Protein general information: Q6QAJ8  
  • Name: Transmembrane protein 220
  • Length: 160  
  • Mass: 17754
• Sequence:

  MAPALWRACNGLMAAFFALAALVQVNDPDAEVWVVVYTIPAVLTLLVGLNPEVTGNVIWKSISAIHILFCTVWAV
  GLASYLLHRTQQNILHEEEGRELSGLVIITAWIILCHSSSKNPVGGRIQLAIAIVITLFPFISWVYIYINKEMRS
  SWPTHCKTVI

• Structural information:
  • Interpro: IPR029377  
  • STRING: ENSP00000339830
• Other Databases: GeneCards:  TMEM220  Malacards:  TMEM220

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)