• Gene id: 387597

Gene Summary

• Gene Symbol: ILDR2   Gene   UCSC   Ensembl
• Aliases: C1orf32, dJ782G3.1
• Gene name: immunoglobulin like domain containing receptor 2
• Alternate names: immunoglobulin-like domain-containing receptor 2,
• Gene location: 1q24.1 (166975539: 166908186)     Exons: 15     NC_000001.11
• OMIM: 618081

Protein Summary

• Protein general information: Q71H61  
  • Name: Immunoglobulin like domain containing receptor 2
  • Length: 639  
  • Mass: 71200
• Sequence:

  MDRVLLRWISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSST
  RAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTP
  DDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCC
  PDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRI
  QADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWS
  GVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHE
  ARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYD
  HSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELT
  RGPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMSLVV

• Structural information:
  • Protein Domains: (21..16-)
    (/note="Ig-like-V-type")
  • Interpro: IPR036179  IPR003599  IPR008664  
  • STRING: ENSP00000271417
• Other Databases: GeneCards:  ILDR2  Malacards:  ILDR2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0048873	homeostasis of number of cells within a tissue	IEA	biological process
GO:0030154	cell differentiation	IEA	biological process
GO:0030073	insulin secretion	IEA	biological process
GO:0009749	response to glucose	IEA	biological process
GO:0031016	pancreas development	IEA	biological process
GO:0005789	endoplasmic reticulum membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881