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Gene id |
3763 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
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Gene Symbol |
KCNJ6 Gene UCSC Ensembl |
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Aliases |
BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, KPLBS, hiGIRK2 |
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Gene name |
potassium inwardly rectifying channel subfamily J member 6 |
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Alternate names |
G protein-activated inward rectifier potassium channel 2, inward rectifier K(+) channel Kir3.2, inward rectifier potassium channel KIR3.2, potassium channel, inwardly rectifying subfamily J, member 6, potassium voltage-gated channel subfamily J member 6, |
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Gene location |
21q22.13 (37916456: 37607372) Exons: 4 NC_000001.11
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Gene summary(Entrez) |
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulat
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OMIM |
600877 |
Protein Summary
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| Associated diseases |
References |
| Epilepsy | GAD: 12458027 |
| Spermatogenesis defects | MIK: 22054410 |
| Keppen-Lubinsky syndrome | KEGG: H02236 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Supports sperm function during fertilization | MIK: 22054410 |
| Teratozoospermia | MIK: 17327269 |
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 22054410 |
Supports s
perm funct
ion during
fertiliza
tion
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Male infertility |
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Show abstract |
| 17327269 |
Teratozoos
permia
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|
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13 (5 controls,
8 cases)
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Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
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Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
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18
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Male infertility |
GSE26881
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Show abstract |
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