• Gene id: 375607

Gene Summary

• Gene Symbol: NAT16   Gene   UCSC   Ensembl
• Aliases: C7orf52
• Gene name: N-acetyltransferase 16 (putative)
• Alternate names: probable N-acetyltransferase 16, N-acetyltransferase 16 (GCN5-related, putative), putative N-acetyltransferase 16, putative N-acetyltransferase C7orf52,
• Gene location: 7q22.1 (101180292: 101170495)     Exons: 5     NC_000007.14
• OMIM: 615783

Protein Summary

• Protein general information: Q8N8M0  
  • Name: Probable N acetyltransferase 16 (EC 2.3.1. )
  • Length: 369  
  • Mass: 40521
• Sequence:

  MKLEASCGTATSEVPKPEKKTARDAEPSSETRPQEVEAEPRSGSGPEAEAEPLDFVVATEREFEEVLAISGGIYG
  GLDYLPSRYHSWLRDPDRTVVLAKRNGGVIALESVNVIDAGETVLVEGLRVAPWERGKGVAGLLQRFCSQLVKRQ
  HPGVKVARLTRDDQLGPRELKKYRLITKQGILLVRFNASALLAGLGARLAALRTSGTFSPLPTEAVSEAGGDVAR
  LLLSPSVQRDVLPGGTIIQDWQPYRPSESNLRLLAAKGLEWRVDSRARPRVLTLCTRPFPIPHGGDGTWRYLNID
  AFGSDGAQVQSQLLWHLQRQAPRLVGLNVMCQLFLEPQLWSQLADFCQVGLGLELVKGYTEQYLLEADI

• Structural information:
  • Protein Domains: (53..18-)
    (/note="N-acetyltransferase-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00532"-)
  • Interpro: IPR016181  IPR000182  
  • Prosite: PS51186
  • STRING: ENSP00000300303
• Other Databases: GeneCards:  NAT16  Malacards:  NAT16

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	IBA	molecular function
GO:0008080	N-acetyltransferase activity	IEA	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0016746	transferase activity, transferring acyl groups	IEA	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881