• Gene id: 375287

Gene Summary

• Gene Symbol: RBM43   Gene   UCSC   Ensembl
• Aliases: C2orf38
• Gene name: RNA binding motif protein 43
• Alternate names: RNA-binding protein 43,
• Gene location: 2q23.3 (151261862: 151247939)     Exons: 11     NC_000002.12

Protein Summary

• Protein general information: Q6ZSC3  
  • Name: RNA binding protein 43 (RNA binding motif protein 43)
  • Length: 357  
  • Mass: 40666
• Sequence:

  MASVLNVKESKAPERTVVVAGLPVDLFSDQLLAVLVKSHFQDIKNEGGDVEDVIYPTRTKGVAYVIFKEKKVAEN
  VIRQKKHWLARKTRHAELTVSLRVSHFGDKIFSSVNAILDLSVFGKEVTLETLVKDLKKKIPSLSFSPLKPNGRI
  SVEGSFLAVKRLRESLLARACSLLEKDRNFTSEERKWNRQNPQRNLQRSNNSLASVRTLVPETARSGEMLVLDTD
  VFLYLKHKCGSYESTLKKFHILSQEKVDGEITTICLKSIQVGSQPNNAKHVKELIEEWSHALYLKLRKETFILEG
  KENREKRMIKRACEQLSSRYLEVLINLYRTHIDIIGSSSDTYLFKKGVMKLIGQKVS

• Structural information:
  • Protein Domains: (15..10-)
    (/note="RRM-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00176"-)
  • Interpro: IPR012677  IPR035979  IPR034463  IPR000504  
  • Prosite: PS50102
  • STRING: ENSP00000331211
• Other Databases: GeneCards:  RBM43  Malacards:  RBM43

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0003723	RNA binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881