|
Gene id |
375189 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PFN4 Gene UCSC Ensembl |
|
Gene name |
profilin family member 4 |
|
Alternate names |
profilin-4, profilin IV, |
|
Gene location |
2p23.3 (24124267: 24114808) Exons: 7 NC_000011.10
|
|
OMIM |
0 |
|
|
|
|
| Associated diseases |
References |
| May regulate testicular actin cytoskeleton dynamics and play a role in acrosome generation and spermatid nuclear shaping | MIK: 15591451 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| May regulate testicular actin cytoskeleton dynamics and play a role in acrosome generation and spermatid nuclear shaping | MIK: 15591451 |
| Non obstructive azoospermia | MIK: 24012201 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 15591451 |
May regula
te testicu
lar actin
cytoskelet
on dynamic
s and play
a role in
acrosome
generation
and sperm
atid nucle
ar shaping
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|