|
Gene id |
373861 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
HILS1 Gene UCSC Ensembl |
|
Aliases |
H1.9 |
|
Gene name |
histone linker H1 domain, spermatid-specific 1 (pseudogene) |
|
Alternate names |
spermatid-specific linker histone H1-like protein, |
|
Gene location |
17q21.33 (50172475: 50171427) Exons: 2 NC_000017.11
|
|
Gene summary(Entrez) |
This locus is the ortholog of a mouse protein-coding gene that displays characteristics of a linker histone and is expressed in nuclei of late maturing spermatids. The human locus is expressed; however, the open reading frame has been disrupted by a frame
|
|
OMIM |
608101 |
|
| Associated diseases |
References |
| Male factor infertility | MIK: 17852044 |
| Asthenozoospermia | MIK: 17852044 |
| Asthenozoospermia | MIK: 17852044 |
| Spermatogenic defects | MIK: 12920187 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17852044 |
Asthenozoo
spermia
|
|
|
170 (70 normozo
ospermia, 100 a
sthenozoospermi
a)
|
Male infertility |
HILS1
TNP1
and TNP2
|
Show abstract |
| 12920187 |
May regula
te gene tr
anscriptio
n, DNA rep
air, and/o
r other ch
romosome p
rocesses d
uring mamm
alian sper
miogenesis
|
|
|
|
Male infertility |
|
Show abstract |
|