|
Gene id |
3625 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
INHBB Gene UCSC Ensembl |
|
Gene name |
inhibin subunit beta B |
|
Alternate names |
inhibin beta B chain, Inhibin, beta-2, activin AB beta polypeptide, activin beta-B chain, inhibin beta B subunit, |
|
Gene location |
2q14.2 (120346135: 120351802) Exons: 2 NC_000002.12
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|
Gene summary(Entrez) |
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activa
|
|
OMIM |
147390 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04060 | Cytokine-cytokine receptor interaction | | hsa04550 | Signaling pathways regulating pluripotency of stem cells | |
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| Associated diseases |
References |
| Cancer | GAD: 19574343 |
| Obesity | GAD: 21552555 |
| Follicular growth and development | INFBASE: 17628551 |
| Premature ovarian failure (POF) | INFBASE: 25954833 |
| Female infertility | INFBASE: 25954833 |
| Male subfertility | MIK: 20923279 |
| Non obstructive azoospermia | MIK: 20923279 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenesis dysfunction | MIK: 27760631 |
| Male infertility | MIK: 27760631 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 27760631 |
Spermatoge
nesis dysf
unction, M
ale infert
ility
|
|
|
|
Male infertility |
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|