• Gene id: 345778

Gene Summary

• Gene Symbol: MTX3   Gene   UCSC   Ensembl
• Gene name: metaxin 3
• Alternate names: metaxin-3,
• Gene location: 5q14.1 (79991261: 79976715)     Exons: 9     NC_000005.10

Protein Summary

• Protein general information: Q5HYI7  
  • Name: Metaxin 3
  • Length: 312  
  • Mass: 35093
• Sequence:

  MAAPLELSCWGGGWGLPSVHSESLVVMAYAKFSGAPLKVNVIDNTWRGSRGDVPILTTEDDMVSQPAKILNFLRK
  QKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYFTVTKPWFASQIPFPLSLILPGRMSKGALNRI
  LLTRGQPPLYHLREVEAQIYRDAKECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQ
  LSNLCRFCDDILSSYFRLSLGGISPAGQETVDANLQKLTQLVNKESNLIEKMDDNLRQSPQLPPRKLPTLKLTPA
  EEENNSFQRLSP

• Structural information:
  • Interpro: IPR036282  IPR040079  IPR017410  IPR033468  IPR019564  
  • STRING: ENSP00000423600
• Other Databases: GeneCards:  MTX3  Malacards:  MTX3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0001401	SAM complex	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005741	mitochondrial outer membrane	IEA	cellular component
GO:0005739	mitochondrion	IEA	cellular component
GO:0015031	protein transport	IEA	biological process
GO:0005739	mitochondrion	IEA	cellular component
GO:0005741	mitochondrial outer membrane	IEA	cellular component
GO:0007007	inner mitochondrial membrane organization	IC	biological process
GO:0003674	molecular_function	ND	molecular function
GO:0140275	MIB complex	HDA	cellular component
GO:0001401	SAM complex	HDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)