|
Gene id |
337 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
APOA4 Gene UCSC Ensembl |
|
Gene name |
apolipoprotein A4 |
|
Alternate names |
apolipoprotein A-IV, apo-AIV, apoA-IV, |
|
Gene location |
11q23.3 (103965803: 103988877) Exons: 10 NC_000012.12
|
|
Gene summary(Entrez) |
Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted
|
|
OMIM |
107690 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04979 | Cholesterol metabolism | | hsa04975 | Fat digestion and absorption | | hsa04977 | Vitamin digestion and absorption | |
|
| Associated diseases |
References |
| Alzheimer's disease | PMID:16013913 |
| Alzheimer's disease | PMID:9272683 |
| Guillain-Barre syndrome | PMID:18343991 |
| Huntington's disease | PMID:21297956 |
| cardiovascular system disease | PMID:21569504 |
| Polyneuropathy | PMID:19589605 |
| Glaucoma | PMID:21078314 |
| Multiple sclerosis | PMID:19383442 |
| Retinal detachment | PMID:19081814 |
| Schizophrenia | PMID:12836058 |
| Myocardial infarction | PMID:7958503 |
| Leber hereditary optic neuropathy | PMID:18061280 |
| Rheumatoid arthritis | PMID:20367977 |
| Chronic kidney disease | PMID:21569504 |
| Crohn's disease | PMID:17206692 |
| intermediate coronary syndrome | PMID:20367977 |
| Diabetic retinopathy | PMID:19081814 |
| Neovascular inflammatory vitreoretinopathy | PMID:19081814 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|