|
Gene id |
30812 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
SOX8 Gene UCSC Ensembl |
|
Gene name |
SRY-box transcription factor 8 |
|
Alternate names |
transcription factor SOX-8, SRY (sex determining region Y)-box 8, SRY-box 8, |
|
Gene location |
16p13.3 (981769: 986978) Exons: 3 NC_000083.6
|
|
Gene summary(Entrez) |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after for
|
|
OMIM |
605923 |
|
| Associated diseases |
References |
| Multiple sclerosis | GAD: 21833088 |
| Reproductive disorderes | MIK: 29373757 |
| Critical regulator of adult Sertoli cell function and is required for both its cytoarchitectural and paracrine interactions with germ cells | MIK: 18342849 |
| Affects male fertility in mouse | MIK: 23595903 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Affects male fertility in mouse | MIK: 23595903 |
| Critical regulator of adult Sertoli cell function and is required for both its cytoarchitectural and paracrine interactions with germ cells | MIK: 18342849 |
| Cryptorchidism | MIK: 28606200 |
| Reproductive anomalies | MIK: 29373757 |
| Male infertility | MIK: 29373757 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29373757 |
Reproducti
ve anomali
es, Male i
nfertility
|
|
|
|
Male infertility |
|
Show abstract |
| 18342849 |
Critical r
egulator o
f adult Se
rtoli cell
function
and is req
uired for
both its c
ytoarchite
ctural and
paracrine
interacti
ons with g
erm cells
|
|
|
|
Male infertility |
|
Show abstract |
| 23595903 |
Affects ma
le fertili
ty in mous
e
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|