|
Gene id |
2937 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
GSS Gene UCSC Ensembl |
|
Aliases |
GSHS, HEL-S-64p, HEL-S-88n |
|
Gene name |
glutathione synthetase |
|
Alternate names |
glutathione synthetase, GSH synthetase, GSH-S, glutathione synthase, |
|
Gene location |
20q11.22 (34956026: 34928431) Exons: 15 NC_000020.11
|
|
Gene summary(Entrez) |
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catal
|
|
OMIM |
601002 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Anemia | KEGG: H00668 |
| Male factor infertility | MIK: 26027266 |
| Glutathione synthetase deficiency | KEGG: H02312 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Male infertility | MIK: 26027266 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 26027266 |
Male infer
tility
|
|
|
90 (60 men with
infertility we
re examined--30
with normal we
ight and 30 wit
h overweight),
30fertile men)
|
Male infertility |
GSH
GR
GPO
GST
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|