• Gene id: 29083

Gene Summary

• Gene Symbol: GTPBP8   Gene   UCSC   Ensembl
• Aliases: HSPC135
• Gene name: GTP binding protein 8 (putative)
• Alternate names: GTP-binding protein 8,
• Gene location: 3q13.2 (40623565: 40624138)     Exons: 1     NC_000023.11

Protein Summary

• Protein general information: Q8N3Z3  
  • Name: GTP binding protein 8
  • Length: 284  
  • Mass: 32147
• Sequence:

  MAAPGLRLGAGRLFEMPAVLERLSRYNSTSQAFAEVLRLPKQQLRKLLYPLQEVERFLAPYGRQDLHLRIFDPSP
  EDIARADNIFTATERNRIDYVSSAVRIDHAPDLPRPEVCFIGRSNVGKSSLIKALFSLAPEVEVRVSKKPGHTKK
  MNFFKVGKHFTVVDMPGYGFRAPEDFVDMVETYLKERRNLKRTFLLVDSVVGIQKTDNIAIEMCEEFALPYVIVL
  TKIDKSSKGHLLKQVLQIQKFVNMKTQGCFPQLFPVSAVTFSGIHLLRCFIASVTGSLD

• Structural information:
  • Protein Domains: (109..28-)
    (/note="EngB-type-G")
  • Interpro: IPR030393  IPR019987  IPR006073  IPR027417  
  • Prosite: PS51706
  • CDD: cd01876
  • STRING: ENSP00000373176
• Other Databases: GeneCards:  GTPBP8  Malacards:  GTPBP8

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005739	mitochondrion	IBA	cellular component
GO:0005525	GTP binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005525	GTP binding	IEA	molecular function
GO:0000166	nucleotide binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005739	mitochondrion	IDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)