• Gene id: 29070

Gene Summary

• Gene Symbol: CCDC113   Gene   UCSC   Ensembl
• Aliases: HSPC065
• Gene name: coiled-coil domain containing 113
• Alternate names: coiled-coil domain-containing protein 113,
• Gene location: 16q21 (58196861: 58283835)     Exons: 16     NC_000016.10
• OMIM: 616070

Protein Summary

• Protein general information: Q9H0I3  
  • Name: Coiled coil domain containing protein 113
  • Length: 377  
  • Mass: 44220
• Sequence:

  MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYA
  QFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEF
  EKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQL
  KIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
  KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLA
  GK

• Structural information:
  • Interpro: IPR025254  
  • STRING: ENSP00000219299
• Other Databases: GeneCards:  CCDC113  Malacards:  CCDC113

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0032991	protein-containing complex	IDA	cellular component
GO:0060271	cilium assembly	IMP	biological process
GO:0034451	centriolar satellite	IMP	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0030030	cell projection organization	IEA	biological process
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0032991	protein-containing complex	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005815	microtubule organizing center	IEA	cellular component
GO:0036064	ciliary basal body	IDA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray