• Gene id: 285343

Gene Summary

• Gene Symbol: TCAIM   Gene   UCSC   Ensembl
• Aliases: C3orf23, TOAG-1, TOAG1
• Gene name: T cell activation inhibitor, mitochondrial
• Alternate names: T-cell activation inhibitor, mitochondrial, tolerance associated gene-1 protein,
• Gene location: 3p21.31 (44337464: 44409447)     Exons: 13     NC_000003.12

Protein Summary

• Protein general information: Q8N3R3  
  • Name: T cell activation inhibitor, mitochondrial (Tolerance associated gene 1 protein) (TOAG 1)
  • Length: 496  
  • Mass: 57925
• Sequence:

  MFCHLRPMRRLCLEKIFPHWFPFSRALSGAEAVNALRPFYFAVHPDFFGQHPVEREINENSLKRLSVYLENLQKP
  GFKSLKPTQLTFYVRETDQSSSDGQEPFSTSGFRAVKFTLHTRDLLSTVLYILNSCSLSVEHIQSLNTNMHTQPL
  KEAKRMPDRPIKWDKSYYSFTGFKDPDEDLEQVSRVETTLTSWLDNNGKSAVKKLKNSLPLRKELDRLKDELSHQ
  LQLSDIRWQRSWGIAHRCSQLHSLSRLAQQNLETLKKAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERL
  PSYFDLQRRLMILEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLLKSRILFHPRSLRGLQMILNSDR
  YAPSLHELGHFNIPTLCDPANLQWFILTKAQQARENMKRKEELKVIENELIQASTKKFSLEKLYKEPSISSIQMV
  DCCKRLLEQSLPYLHGMHLCISHFYSVMQDGDLCIPWNWKNGEAIK

• Structural information:
  • Interpro: IPR028031  IPR027989  IPR027986  
  • STRING: ENSP00000341539
• Other Databases: GeneCards:  TCAIM  Malacards:  TCAIM

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005739	mitochondrion	IBA	cellular component
GO:0005739	mitochondrion	IEA	cellular component
GO:0005739	mitochondrion	IDA	cellular component
GO:0005739	mitochondrion	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881