• Gene id: 284948

Gene Summary

• Gene Symbol: SH2D6   Gene   UCSC   Ensembl
• Gene name: SH2 domain containing 6
• Alternate names: SH2 domain-containing protein 6,
• Gene location: 2p11.2 (85418930: 85437028)     Exons: 25     NC_000002.12
• OMIM: 300111

Protein Summary

• Protein general information: Q7Z4S9  
  • Name: SH2 domain containing protein 6
  • Length: 175  
  • Mass: 19279
• Sequence:

  MYASSYPPPPQLSPRSHLCPPPPHPTPPQLNNLLLLEGRKSSLPSVAPTGSASAAEDSDLLTQPWYSGNCDRYAV
  ESALLHLQKDGAYTVRPSSGPHGSQPFTLAVLLRGRVFNIPIRRLDGGRHYALGREGRNREELFSSVAAMVQHFM
  WHPLPLVDRHSGSRELTCLLFPTKP

• Structural information:
  • Protein Domains: (65..17-)
    (/note="SH2-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00191"-)
  • Interpro: IPR000980  IPR036860  
  • Prosite: PS50001
  • STRING: ENSP00000341867
• Other Databases: GeneCards:  SH2D6  Malacards:  SH2D6

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0035556	intracellular signal transduction	IBA	biological process
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881