• Gene id: 284369

Gene Summary

• Gene Symbol: SIGLECL1   Gene   UCSC   Ensembl
• Aliases: C19orf75, SIGLEC23P, SIGLECP7
• Gene name: SIGLEC family like 1
• Alternate names: SIGLEC family-like protein 1, sialic acid binding Ig-like lectin, pseudogene 7,
• Gene location: 19q13.41 (51251057: 51269329)     Exons: 8     NC_000019.10
• OMIM: 0

Protein Summary

• Protein general information: Q8N7X8  
  • Name: SIGLEC family like protein 1
  • Length: 197  
  • Mass: 21283
• Sequence:

  MLPLLQLVPAKLLNSSCSLEKTLQCSCSFHGIPTPSVQWWMGGVPVGVDGMDGSLQVTSTMLGPWANSTISLTEE
  PEMGMRLLCEGKNQNGTHALSILLMSRKSSLAAQAFVKGLIQGAIYAGIVIALLFLCLLPLIVKHIRKKQAKKAA
  AIRAKKSSKVRASQELEMSLKPEEPGKPVVATFSESRILEKQDKRAS

• Structural information:
  • Interpro: IPR036179  IPR013783  
• Other Databases: GeneCards:  SIGLECL1  Malacards:  SIGLECL1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0033691	sialic acid binding	IBA	molecular function
GO:0005886	plasma membrane	IBA	cellular component
GO:0007155	cell adhesion	IBA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)