• Gene id: 283849

Gene Summary

• Gene Symbol: EXOC3L1   Gene   UCSC   Ensembl
• Aliases: EXOC3L
• Gene name: exocyst complex component 3 like 1
• Alternate names: exocyst complex component 3-like protein, protein Jiangli,
• Gene location: 16q22.1 (67190135: 67184378)     Exons: 14     NC_000016.10
• OMIM: 601327

Protein Summary

• Protein general information: Q86VI1  
  • Name: Exocyst complex component 3 like protein (Protein Jiangli)
  • Length: 746  
  • Mass: 81678
• Sequence:

  MDSAAKDEMQPALSPGPEWPEQERAEQLARGAALKWASGIFYRPEQLARLGQYRSREVQRTCSLESRLKSVMQSY
  LEGVQTGVWQLAQAIEVVQGTREALSQARGLLQGMSQALQTLEPLRERVAQHKQLQALSHLLPRLRAVPAAVSHT
  QTLIDGQQFLEAYVSLRELEQLREDTWAPLGGLELPVFQGLDLLFEALGQAVEAAAGAAGKLAREDPALLVAAVR
  VAEVETGRTTPLGQVPRDWRQRCLRALQEGLEQAHFGSPLLPAPGALPGWLEALRVALPVELATAEALVAPCCPP
  QYNVVQLWAHTLHSGLRRSLQNLLAGPELEAADAFALLHWALHVYLGQEMMGSLELGPEADVSQLEPLLTLENIE
  QLEATFVANIQASVSQWLQNALDGEVAEWGREHGPNTDPSGSYYSPMPAIVLQILEENIRVASLVSESLQQRVHG
  MALSELGTFLRSFSDALIRFSRDHFRGKSMAPHYVPYLLAALNHKSALSSSVSVLQLDGAPSGALAPVEAALDEL
  QRRIYRLVLEALQAELQPLFADLPSRQWLSSPELLQSVCERTGRFCRDFWRVRNPTVQLLLAEAERAVVLQYLSA
  LMQGRLVCRGADERTQAAERLRHDAAQLQQLFLSLGLEENAHCAPVLLALRELLNLRDPALLGLEVAGLRQQFPD
  VSEDHVSALLGLRGDLSREQHLAALSSLQAALPPSPRASRRVLFSLVPAPALAPASCLPSGSCARALLLAE

• Structural information:
  • Interpro: IPR010326  
  • STRING: ENSP00000325674
• Other Databases: GeneCards:  EXOC3L1  Malacards:  EXOC3L1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0051601	exocyst localization	IBA	biological process
GO:0006887	exocytosis	IBA	biological process
GO:0000149	SNARE binding	IBA	molecular function
GO:0000145	exocyst	IBA	cellular component
GO:0000145	exocyst	IEA	cellular component
GO:0006887	exocytosis	IEA	biological process
GO:0031410	cytoplasmic vesicle	IEA	cellular component
GO:0006887	exocytosis	IEA	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0030141	secretory granule	IEA	cellular component
GO:0000145	exocyst	IEA	cellular component
GO:0006887	exocytosis	IEA	biological process
GO:0030072	peptide hormone secretion	IEA	biological process
GO:0030133	transport vesicle	IEA	cellular component
GO:0030072	peptide hormone secretion	ISS	biological process
GO:0003674	molecular_function	ND	molecular function
GO:0006887	exocytosis	ISS	biological process
GO:0000145	exocyst	ISS	cellular component
GO:0030141	secretory granule	ISS	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R