• Gene id: 283635

Gene Summary

• Gene Symbol: FAM177A1   Gene   UCSC   Ensembl
• Aliases: C14orf24
• Gene name: family with sequence similarity 177 member A1
• Alternate names: protein FAM177A1,
• Gene location: 14q13.2 (149129623: 149173731)     Exons: 18     NC_000003.12
• Gene summary(Entrez): This gene encodes a member of a conserved protein family. Alternative splicing results in multiple transcript variants. This gene is thought to be associated with susceptibility to juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]

Protein Summary

• Protein general information: Q8N128  
  • Name: Protein FAM177A1
  • Length: 213  
  • Mass: 23757
• Sequence:

  MDQEPVGGVERGEAVAASGAAAAAAFGESAGQMSNERGFENVELGVIGKKKKVPRRVIHFVSGETMEEYSTDEDE
  VDGLEKKDVLPTVDPTKLTWGPYLWFYMLRAATSTLSVCDFLGEKIASVLGISTPKYQYAIDEYYRMKKEEEEEE
  EENRMSEEAEKQYQQNKLQTDSIVQTDQPETVISSSFVNVNFEMEGDSEVIMESKQNPVSVPP

• Structural information:
  • Interpro: IPR028260  
  • STRING: ENSP00000280987
• Other Databases: GeneCards:  FAM177A1  Malacards:  FAM177A1

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881