• Gene id: 283373

Gene Summary

• Gene Symbol: ANKRD52   Gene   UCSC   Ensembl
• Aliases: ANKRD33
• Gene name: ankyrin repeat domain 52
• Alternate names: serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C, CVWG5837, PP6-ARS-C, ankyrin repeat domain 33, ankyrin repeat domain-containing protein 52, protein phosphatase 6 ankyrin repeat subunit C, serine/threonine-protein phosphatase 6 regula,
• Gene location: 12q13.3 (56258390: 56237806)     Exons: 29     NC_000012.12
• OMIM: 610383

Protein Summary

• Protein general information: Q8NB46  
  • Name: Serine/threonine protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6 ARS C) (Serine/threonine protein phosphatase 6 regulatory subunit ARS C) (Ankyrin repeat domain containing protein 52)
  • Length: 1076  
  • Mass: 115077
• Sequence:

  MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWL
  TPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHS
  GHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYL
  LRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVN
  YQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFP
  LHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLR
  RRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTPSSHDAEEDEPLKESR
  RKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEA
  LKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSG
  ERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCR
  DFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFT
  PLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAE
  NGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLAS
  VVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKPFPPKDAVSPFSFSLLKNCSIAAAKTVGGCG
  ALPHGASCPYSQERPGAIGLDGCYSE

• Structural information:
  • Interpro: IPR002110  IPR020683  IPR036770  
  • Prosite: PS50297 PS50088
  • STRING: ENSP00000267116
• Other Databases: GeneCards:  ANKRD52  Malacards:  ANKRD52

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Hypospermatogenesis	MIK: 28361989

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray