• Gene id: 26150

Gene Summary

• Gene Symbol: RIBC2   Gene   UCSC   Ensembl
• Aliases: C22orf11, TRIB
• Gene name: RIB43A domain with coiled-coils 2
• Alternate names: RIB43A-like with coiled-coils protein 2,
• Gene location: 22q13.31 (45413692: 45432508)     Exons: 10     NC_000022.11
• OMIM: 0

Protein Summary

• Protein general information: Q9H4K1  
  • Name: RIB43A like with coiled coils protein 2
  • Length: 382  
  • Mass: 45427
• Sequence:

  MGSQTMAVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEMR
  QNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGED
  LNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQ
  AIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEK
  LRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQPTGDYFT
  QFNTGSR

• Structural information:
  • Interpro: IPR008805  
  • STRING: ENSP00000483356
• Other Databases: GeneCards:  RIBC2  Malacards:  RIBC2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	HDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R