• Gene id: 26127

Gene Summary

• Gene Symbol: FGFR1OP2   Gene   UCSC   Ensembl
• Aliases: HSPC123-like, WIT3.0
• Gene name: FGFR1 oncogene partner 2
• Alternate names: FGFR1 oncogene partner 2, fibroblast growth factor receptor 1 oncogene partner 2, wound inducible transcript 3.0,
• Gene location: 12p11.23 (26938371: 26966647)     Exons: 7     NC_000012.12
• OMIM: 608858

Protein Summary

• Protein general information: Q9NVK5  
  • Name: FGFR1 oncogene partner 2
  • Length: 253  
  • Mass: 29426
  • Tissue specificity: Expressed in bone marrow, spleen and thymus.
• Sequence:

  MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQ
  IRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASR
  HILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF
  LNLRKDDASESTSLSALVTNSDLSLRKS

• Structural information:
  • Interpro: IPR008555  
  • STRING: ENSP00000229395
• Other Databases: GeneCards:  FGFR1OP2  Malacards:  FGFR1OP2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0009611	response to wounding	IBA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0042802	identical protein binding	IEA	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0042060	wound healing	IEA	biological process
GO:0009611	response to wounding	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray