• Gene id: 25864

Gene Summary

• Gene Symbol: ABHD14A   Gene   UCSC   Ensembl
• Aliases: DORZ1
• Gene name: abhydrolase domain containing 14A
• Alternate names: protein ABHD14A, abhydrolase domain-containing protein 14A, alpha/beta hydrolase domain-containing protein 14A,
• Gene location: 3p21.2 (51975063: 51981195)     Exons: 5     NC_000003.12
• OMIM: 618771

Protein Summary

• Protein general information: Q9BUJ0  
  • Name: Protein ABHD14A (EC 3. . . ) (Alpha/beta hydrolase domain containing protein 14A) (Abhydrolase domain containing protein 14A)
  • Length: 271  
  • Mass: 29765
• Sequence:

  MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTSCLWGDPNVTVLAGLT
  PGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPSKEASTEAGRA
  ALLERALRDLEVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILYGELDHIL
  ARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP

• Structural information:
  • Interpro: IPR029058  IPR000073  
  • STRING: ENSP00000273596
• Other Databases: GeneCards:  ABHD14A  Malacards:  ABHD14A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0016787	hydrolase activity	IEA	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881